Surfactant Replacement Therapy for RDS, Early Rescue Therapy should be practiced:

Beraksurf® is a choice medicine for treatment of newborn infants with Respiratory Distress Syndrome (IRDS). First dose needs to be given as soon as diagnosis of RDS is made. RDS in a premature infant is defined as respiratory distress requiring more than 30% oxygen delivered by positive pressure using either Nasal CPAP or an ET Tube with a chest radiograph that has diffuse infiltrates with a ground glass granular appearance with air bronchograms. Ideally the dose should be given within 1 hr. of birth but definitely before 2 hours of age. A repeat dose should be given within 4 - 12 hours if the patient is still intubated and requiring more than 30 to 40% oxygen.

Prophylactic therapy (before chest radiograph) can be considered in patients with respiratory distress who are intubated and are < 26 weeks gestation. Other indications:

- acute lung injury/acute respiratory distress syndrome of adults